Department of Biochemistry, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Cell Biochem Funct. 2011 Mar;29(2):96-101. doi: 10.1002/cbf.1726. Epub 2011 Feb 9.
The burning of incense is an important source of indoor air pollution in Asia. We assessed the effect of long-term exposure to incense smoke on the body weight and levels of circulating glucose, triglycerides, total cholesterol, HDL-cholesterol, insulin, adiponectin and leptin in Wistar albino rats. Two groups of rats were used. First group (n = 12) was exposed daily to incense smoke for 4 months at the rate of 4 g day(-1) in the exposure chamber. Another group of rats (n = 12), was used as non-exposed control. Blood samples were collected from all animals after 4, 8, 12 and 16 weeks of exposure. Serum glucose, triglycerides, total cholesterol and HDL-cholesterol, LDL-cholesterol insulin, adiponectin and leptin were measured. Our results showed that incense smoke exposure was associated with decreased weight gain and the adverse metabolic changes of increased triglycerides and decreased HDL-cholesterol concentrations. Exposure to incense was also associated with a transient increase of leptin levels. Taken together, these data suggest that incense smoke influences metabolism adversely in rats. The effect of incense smoke on human health and the underlying mechanisms need to be studied further.
熏香燃烧是亚洲室内空气污染的一个重要来源。我们评估了长期暴露于熏香烟雾对 Wistar 白化大鼠体重和循环葡萄糖、甘油三酯、总胆固醇、高密度脂蛋白胆固醇、胰岛素、脂联素和瘦素水平的影响。使用了两组大鼠。第一组（n=12）在暴露室内每天以 4 克/天的速度暴露于熏香烟雾中，持续 4 个月。另一组大鼠（n=12）作为非暴露对照。在暴露 4、8、12 和 16 周后，从所有动物收集血液样本。测量血清葡萄糖、甘油三酯、总胆固醇和高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、胰岛素、脂联素和瘦素。我们的结果表明，熏香烟雾暴露与体重增加减少以及甘油三酯升高和高密度脂蛋白胆固醇浓度降低等不良代谢变化有关。暴露于熏香烟雾还与瘦素水平的短暂升高有关。总之，这些数据表明，熏香烟雾会对大鼠的代谢产生不利影响。熏香烟雾对人类健康的影响和潜在机制需要进一步研究。
