Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli County, Taiwan, R O C.
Org Lett. 2011 Mar 4;13(5):896-9. doi: 10.1021/ol102947u. Epub 2011 Feb 10.
The autoxidative annulation cascade promoted by an α-cyano β-TMS-capped alkynyl cycloalkanone system under catalysis with pyridine in one oxygen atmosphere has proven to be highly viable. On the basis of this newly developed protocol, a variety of highly functionalized bicyclic frameworks can be effectively constructed.
在一个氧气气氛中，吡啶催化下，α-氰基β-TMS-封端的炔基环烷酮体系促进的自动氧化环化级联反应已被证明是非常可行的。在此新开发的反应条件下，可以有效地构建各种高官能化的双环骨架。
