Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli County 35053, Taiwan, R. O. C.
Org Lett. 2012 Dec 7;14(23):6024-7. doi: 10.1021/ol3028972. Epub 2012 Nov 28.
The radical cascade protocol of the α-cyano α-TMS/aryl-capped alkynyl aryl ketones promoted by tert-butyl hydroperoxide under catalysis with tetrabutylammonium iodide in refluxing benzene has been developed, leading to the construction of a variety of highly functionalized [6,6,5] tricyclic frameworks in an efficient manner.
已开发出在回流苯中，叔丁基过氧化氢促进下，α-氰基α-TMS/芳基封端炔基芳基酮的自由基级联反应协议，并在四丁基碘化铵催化下，高效构建各种高度官能化的[6,6,5]三环骨架。
