School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan, 030006, China.
Org Biomol Chem. 2011 Apr 7;9(7):2345-9. doi: 10.1039/c0ob00983k. Epub 2011 Feb 11.
A water-soluble fluorescent sensor, 1, based on the "receptor-spacer-fluorophore" [2-(2'-aminophenyl)benzoxazole-amide-2-picolylamine] sensor platform, demonstrates the high sensitivity for Zn(2+) with a 25-fold fluorescence enhancement upon chelation to Zn(2+) and also exhibits high selectivity to Zn(2+) over other metal ions. X-ray crystal structure of Zn(2+) complex reveals that the amide oxygen (O2) cooperates with 2-picolylamine unit (N3, N4) as a receptor bind Zn(2+).
一种基于“受体-间隔基-荧光团”[2-(2'-氨基苯基)苯并恶唑酰胺-2-吡啶基乙胺]传感器平台的水溶性荧光传感器 1，对 Zn(2+)表现出高灵敏度，与 Zn(2+)螯合后荧光增强 25 倍，并且对 Zn(2+)具有高选择性。Zn(2+)配合物的 X 射线晶体结构表明酰胺氧 (O2)与 2-吡啶基乙胺单元 (N3、N4)协同作为受体结合 Zn(2+)。
