Bulaev V M, Koplik E V
Biull Eksp Biol Med. 1978 Oct;86(10):450-2.
As revealed in acute experiments on rats bradykinin applied microiontophoretically produced neuronal activation in the sensory-motor region of the rat brain cortex. Morphine applied iontophoretically prevented bradykinin effect. It is suggested that bradykinin interacts with opiate receptors in the cortical neurones.