A new algorithm that combines gene expression and copy number alterations to identify driver genes and their possible function is reported. This was applied to melanoma samples, and vesicular trafficking was found to be an important process in this type of cancer.
报道了一种新的算法,该算法结合基因表达和拷贝数改变来识别驱动基因及其可能的功能。该算法应用于黑色素瘤样本,发现囊泡运输是这种癌症的一个重要过程。