Department of Anatomy, Physiology, and Cell Biology, School of Veterinary Medicine, University of California-Davis, Davis, CA, USA. Tel.: +1 530 754 0146; Fax: +1 530 753 7690;
Brief Funct Genomics. 2013 Sep;12(5):391-6. doi: 10.1093/bfgp/elt019. Epub 2013 Jun 20.
Microarray technologies provide high-throughput analysis of genes that are differentially expressed in humans and other species, and thereby provide a means to measure how biological systems are altered during development or disease states. Within, we review how high-throughput genomic technologies have increased our understanding about the molecular complexity of breast cancer, identified distinct molecular phenotypes and how they can be used to increase the accuracy of predicted clinical outcome.
微阵列技术提供了高通量分析人类和其他物种中差异表达基因的方法，从而提供了一种测量生物系统在发育或疾病状态下如何改变的手段。在这里，我们回顾了高通量基因组技术如何增加我们对乳腺癌分子复杂性的理解，确定了不同的分子表型以及如何利用它们来提高预测临床结果的准确性。
