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性别差异在心房颤动患者治疗中的作用:基于人群的当地卫生区研究。

Sex differences in the treatment of patients with atrial fibrillation: population-based study in a local health district.

机构信息

Sección de Urgencias, Área de Urgencias, Hospital Clínic, Barcelona, España.

出版信息

Rev Esp Cardiol. 2011 Mar;64(3):233-6. doi: 10.1016/j.recesp.2010.04.002. Epub 2011 Feb 15.

DOI:10.1016/j.recesp.2010.04.002
PMID:21324575
Abstract

Differences in the treatment of atrial fibrillation between men and women were investigated by using patients in a local health district as a reference population. The study included 688 patients (359 female) who presented with atrial fibrillation. Women were older, more frequently had heart failure, and were more often functionally dependent than men. With regards to the management of atrial fibrillation, women were prescribed digoxin more frequently than men, but underwent electrical cardioversion less often, were less frequently seen by a cardiologist, and understood less about their treatment. After stratifying the findings by age and adjusting for heart failure and the degree of functional dependence, it was observed that women aged over 85 years were prescribed digoxin more often than men, while women aged under 65 years underwent cardioversion less often than men. In conclusion, gender differences observed in the treatment of atrial fibrillation cannot be fully explained by differences in clinical characteristics between men and women in the population.

摘要

本研究以当地某一卫生区域的患者作为参照人群,调查了男女之间在心房颤动治疗上的差异。该研究纳入了 688 名心房颤动患者(女性 359 名)。与男性相比,女性年龄更大,心力衰竭更为常见,且功能依赖性更强。在心房颤动的治疗方面,女性比男性更常服用地高辛,但电复律治疗的比例更低,较少接受心脏病专家的诊治,对治疗的了解也更少。将这些发现按年龄分层,并调整心力衰竭和功能依赖性程度后发现,85 岁以上的女性比男性更常服用地高辛,而 65 岁以下的女性比男性更少接受电复律治疗。综上,人群中男女之间的临床特征差异并不能完全解释在心房颤动治疗中观察到的性别差异。

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引用本文的文献

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Sex differences in management and outcomes of patients with atrial fibrillation in the Middle East: Gulf survey of atrial fibrillation events (Gulf SAFE).中东地区心房颤动患者管理及预后的性别差异:海湾地区心房颤动事件调查(海湾地区心房颤动事件安全调查)
PLoS One. 2017 May 17;12(5):e0175405. doi: 10.1371/journal.pone.0175405. eCollection 2017.
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Gender differences related to the presence of atrial fibrillation in older hypertensive patients.老年高血压患者心房颤动存在与否相关的性别差异。
World J Cardiol. 2013 May 26;5(5):124-31. doi: 10.4330/wjc.v5.i5.124.
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Trends in utilization of management strategies for newly diagnosed atrial fibrillation patients in the United States: 1999 to 2008.
1999年至2008年美国新诊断房颤患者管理策略的使用趋势
J Pharm Pract. 2012 Apr;25(2):151-9. doi: 10.1177/0897190011424803. Epub 2011 Nov 18.