HIV 不一致关系对乌干达拉凯新 HIV 感染的贡献。
The contribution of HIV-discordant relationships to new HIV infections in Rakai, Uganda.
机构信息
Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland, USA.
出版信息
AIDS. 2011 Mar 27;25(6):863-5. doi: 10.1097/QAD.0b013e3283448790.
Abstract
We determined HIV infections in the Rakai cohort before (82/9434) and after (131/13082) the availability of antiretroviral therapy (ART). The proportions of total HIV infections pre-ART and post-ART were 18.3% and 13.7%, respectively, among identifiable HIV-discordant couples, 23.2% and 26.0%, respectively, in concordant HIV-negative couples, 29.3% and 17.6% in married persons with unknown partner status, and 29.3% and 42.7% in the unmarried. Voluntary counseling and testing targeting discordant couples is unlikely to have a substantial impact in this setting.
摘要
我们确定了 Rakai 队列中在（82/9434）抗逆转录病毒疗法（ART）可用之前和之后（131/13082）的艾滋病毒感染情况。在可识别的 HIV 不一致夫妇中，分别有 18.3%和 13.7%的 HIV 感染在 ART 前和 ART 后，在 HIV 阴性一致夫妇中，分别有 23.2%和 26.0%，在婚姻状况不明的已婚者中，分别有 29.3%和 17.6%，在未婚者中，分别有 29.3%和 42.7%。针对不一致夫妇的自愿咨询和检测不太可能对这种情况产生重大影响。
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本文引用的文献
1
Heterosexual HIV-1 transmission after initiation of antiretroviral therapy: a prospective cohort analysis.
Lancet. 2010 Jun 12;375(9731):2092-8. doi: 10.1016/S0140-6736(10)60705-2. Epub 2010 May 26.
2
A tale of two-component generalised HIV epidemics.
Lancet. 2010 Mar 20;375(9719):964-6. doi: 10.1016/S0140-6736(10)60416-3.
3
Trends in marriage and time spent single in sub-Saharan Africa: a comparative analysis of six population-based cohort studies and nine Demographic and Health Surveys.
Sex Transm Infect. 2009 Apr;85 Suppl 1(Suppl_1):i64-71. doi: 10.1136/sti.2008.034249.
4
Heterosexual risk of HIV-1 infection per sexual act: systematic review and meta-analysis of observational studies.
Lancet Infect Dis. 2009 Feb;9(2):118-29. doi: 10.1016/S1473-3099(09)70021-0.
5
New heterosexually transmitted HIV infections in married or cohabiting couples in urban Zambia and Rwanda: an analysis of survey and clinical data.
Lancet. 2008 Jun 28;371(9631):2183-91. doi: 10.1016/S0140-6736(08)60953-8.
6
Universal HIV testing and counselling in Africa.
Lancet. 2008 Jun 28;371(9631):2148-50. doi: 10.1016/S0140-6736(08)60929-0.
7
Effect of aciclovir on HIV-1 acquisition in herpes simplex virus 2 seropositive women and men who have sex with men: a randomised, double-blind, placebo-controlled trial.
Lancet. 2008 Jun 21;371(9630):2109-19. doi: 10.1016/S0140-6736(08)60920-4.
8
Late marriage and the HIV epidemic in sub-Saharan Africa.
Popul Stud (Camb). 2007 Mar;61(1):73-83. doi: 10.1080/00324720601048343.
9
Rates of HIV-1 transmission per coital act, by stage of HIV-1 infection, in Rakai, Uganda.
J Infect Dis. 2005 May 1;191(9):1403-9. doi: 10.1086/429411. Epub 2005 Mar 30.
10
HIV status and union dissolution in sub-Saharan Africa: the case of Rakai, Uganda.
Demography. 2004 Aug;41(3):465-82. doi: 10.1353/dem.2004.0025.
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