Department of Cardiology and Angiology, Marienhospital Herne, Ruhr University Bochum, Herne, Germany.
Int J Med Sci. 2011 Feb 1;8(2):106-13. doi: 10.7150/ijms.8.106.
Strain rate imaging techniques have been proposed for the detection of ischemic or viable myocardium in coronary artery disease, which is still a challenge in clinical cardiology. This retrospective comparative study analyzed regional left ventricular function and scaring with two-dimensional strain (2DS) in the first 4 to 10 days after acute anterior myocardial infarction (AMI).
The study population consisted of 32 AMI patients with an LAD occlusion and successful reperfusion. The assessment of peak systolic 2DS and peak systolic strain rate (SR) was performed segment-oriented with the angle-independent speckle tracking algorithm Velocity Vector Imaging (VVI). The infarcted, adjacent and non-infarcted segments were revealed by late enhancement MRI (LE-MRI), which was used as reference for the comparison with 2DS. The infarcted segments showed a significant decrease of tissue velocities, 2DS and SR in comparison to the non-affected segments.
2DS and SR as assessed by VVI seem to be a suitable approach for echocardiographic quantification of global and regional myocardial function as well as a promising tool for multimodal risk stratification after anterior AMI.
应变率成像技术已被提出用于检测冠心病中的缺血或存活心肌，这在临床心脏病学中仍然是一个挑战。这项回顾性对比研究分析了急性前壁心肌梗死（AMI）后 4 至 10 天内二维应变（2DS）的局部左心室功能和瘢痕。
研究人群包括 32 例 LAD 闭塞和成功再灌注的 AMI 患者。使用角度独立的斑点追踪算法 Velocity Vector Imaging（VVI）进行节段定向评估，以获得收缩期峰值 2DS 和收缩期峰值应变率（SR）。通过晚期增强 MRI（LE-MRI）显示梗死、相邻和非梗死节段，将其作为与 2DS 比较的参考。与非受累节段相比，梗死节段的组织速度、2DS 和 SR 明显下降。
VVI 评估的 2DS 和 SR 似乎是一种适用于超声心动图定量评估整体和局部心肌功能的方法，也是前壁 AMI 后多模态风险分层的有前途的工具。
