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[2009年甲型H1N1流感感染中的短暂性胼胝体病变]

[Transient splenial lesion in influenza A H1N1 2009 infection].

作者信息

Linden K, Moser O, Simon A, Eis-Hübinger A-M, Fleischhack G, Born M, Tschampa H, Rosenbaum T, Köster B, Lentze M

机构信息

Zentrum für Kinderheilkunde, Universitätsklinikum Bonn, Adenauerallee 119, Bonn, Germany.

出版信息

Radiologe. 2011 Mar;51(3):220-2. doi: 10.1007/s00117-011-2131-0.

DOI:10.1007/s00117-011-2131-0
PMID:21328046
Abstract

Severe neurologic complications have been rarely reported during novel pandemic influenza A(H1N1) virus infections. We describe the case of an 10-year-old boy with new onset seizures and proven influenza A(H1N1) 2009 infection showing a reversible hyperintense lesion in the splenium of the corpus callosum on T2-weighted and FLAIR magnetic resonance images without contrast enhancement. Transient splenial lesions have been described in the context of virus encephalopathy and do not require specific treatment.

摘要

新型甲型H1N1流感病毒感染期间严重神经系统并发症鲜有报道。我们描述了一例10岁男孩的病例,该男孩新发癫痫,确诊为2009年甲型H1N1流感感染,在T2加权和液体衰减反转恢复序列磁共振图像上胼胝体压部出现可逆性高信号病变,无强化表现。病毒脑病时曾有短暂性胼胝体病变的描述,且无需特殊治疗。

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Acute necrotizing encephalopathy in a child with H1N1 influenza infection.儿童感染 H1N1 流感导致急性坏死性脑病。
Pediatr Radiol. 2010 Feb;40(2):200-5. doi: 10.1007/s00247-009-1487-z. Epub 2009 Dec 18.
2
Detection of influenza A(H1N1)v virus by real-time RT-PCR.通过实时逆转录聚合酶链反应检测甲型H1N1流感病毒
Euro Surveill. 2009 Sep 10;14(36):19329.
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Neurologic complications associated with novel influenza A (H1N1) virus infection in children - Dallas, Texas, May 2009.2009年5月德克萨斯州达拉斯市儿童感染新型甲型H1N1流感病毒相关的神经系统并发症
与甲型流感 A(H1N1)pdm09 相关的神经事件。
Influenza Other Respir Viruses. 2014 May;8(3):339-46. doi: 10.1111/irv.12241.
MMWR Morb Mortal Wkly Rep. 2009 Jul 24;58(28):773-8.
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Two newly proposed infectious encephalitis/encephalopathy syndromes.两种新提出的感染性脑炎/脑病综合征。
Brain Dev. 2009 Aug;31(7):521-8. doi: 10.1016/j.braindev.2009.02.012. Epub 2009 Mar 31.
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Focal lesions in the splenium of the corpus callosum in patients with epilepsy.癫痫患者胼胝体压部的局灶性病变。
Epilepsia. 2009 Jun;50(6):1354-60. doi: 10.1111/j.1528-1167.2008.01800.x. Epub 2008 Oct 6.
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Reversible splenial lesion in influenza virus encephalopathy.流感病毒脑病中的可逆性胼胝体病变
Pediatr Neurol. 2007 Dec;37(6):431-4. doi: 10.1016/j.pediatrneurol.2007.08.008.
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Transient splenial lesion of the corpus callosum in clinically mild influenza-associated encephalitis/encephalopathy.临床症状轻微的流感相关脑炎/脑病中胼胝体的短暂性胼胝体病变
AJNR Am J Neuroradiol. 2006 Oct;27(9):1983-6.
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Reversible splenial lesion in clinically mild encephalitis.临床轻度脑炎中的可逆性胼胝体病变
Singapore Med J. 2005 Dec;46(12):726-30.
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Transient lesion in the splenium of the corpus callosum and antiepileptic drug withdrawal.胼胝体压部的短暂性病变与抗癫痫药物撤药
Neurology. 2005 Oct 11;65(7):1032-6. doi: 10.1212/01.wnl.0000179301.96652.27.
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Diffusion-weighted imaging abnormalities in the splenium after seizures.癫痫发作后胼胝体压部的扩散加权成像异常。
Epilepsia. 2003 Jun;44(6):852-4. doi: 10.1046/j.1528-1157.2003.40902.x.