急性吉兰-巴雷综合征患者血液和脑脊液中的淋巴细胞亚群

Lymphocyte subpopulations in blood and cerebrospinal fluid from patients with acute Guillain-Barré syndrome.

作者信息

Nyland H, Nacess A

出版信息

Eur Neurol. 1978;17(5):247-52. doi: 10.1159/000114953.

Abstract

The numbers of T and B lymphocytes were determined in blood and cerebrospinal fluid (CSF) from 25 patients with acute Guillain-Barré syndrome and from 30 controls. The relative and absolute number of T lymphocytes in blood was decreased in the patient group (mean 48 +/- 2% and 947 +/- 71/mm3 compared to 66 +/- 2% and 1,381 +/- 93/mm3 in controls). Correspondingly, the number of B lymphocytes was increased (mean 37 +/- 2% and 758 +/- 75/mm3 compared to 25 +/- 2% and 580 +/- 45/mm3 in controls). In the CSF the number of T lymphocytes was increased (85.0 +/- 2.2% compared to 76.9 +/- 2.4% in controls).

摘要

对25例急性吉兰-巴雷综合征患者及30名对照者的血液和脑脊液（CSF）中的T淋巴细胞和B淋巴细胞数量进行了测定。患者组血液中T淋巴细胞的相对数和绝对数均降低（平均值分别为48±2%和947±71/mm³，而对照组分别为66±2%和1381±93/mm³）。相应地，B淋巴细胞数量增加（平均值分别为37±2%和758±75/mm³，而对照组分别为25±2%和580±45/mm³）。脑脊液中T淋巴细胞数量增加（85.0±2.2%，而对照组为76.9±2.4%）。