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[格林-巴利综合征中T淋巴细胞与脑脊液的细胞动力学观察]

[Cyto-dynamic observations on T lymphocytes and the CSF in Guillain-Barre syndrome].

作者信息

Diao K P

出版信息

Zhonghua Shen Jing Jing Shen Ke Za Zhi. 1989 Feb;22(1):26-8, 62.

PMID:2805974
Abstract

We have examined by ANAL for 107 times in 45 cases and the cytology of CSF in 92 times for acute infectious polyneuritis. The count of T-lymphocytes in severe and most severe types had a marked decrease comparing with the light and moderate types. The patients with a course of disease less than seven days had a significant decreasing to comparing with the more than seven days. The immune complex (IgG, IgM, Cs) had a distinct decreasing. The cytology of CSF showed that the lymphocytes were decreasing but the monocytes and the macrophages increased. We considered that there were not only cellular immunity dysfunction, but also the humoral immunity dysfunction. Using of hormones in this disease is not suitable.

摘要

我们对45例急性感染性多发性神经炎患者进行了107次ANAL检查,并对其脑脊液进行了92次细胞学检查。重度和极重度类型的T淋巴细胞计数与轻度和中度类型相比明显降低。病程小于7天的患者与病程大于7天的患者相比,T淋巴细胞计数显著降低。免疫复合物(IgG、IgM、Cs)明显减少。脑脊液细胞学检查显示淋巴细胞减少,但单核细胞和巨噬细胞增多。我们认为,不仅存在细胞免疫功能障碍,而且存在体液免疫功能障碍。在这种疾病中使用激素是不合适的。

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