Sturm V
Augenklinik, Universitätsspital Zürich, Zürich.
Praxis (Bern 1994). 2011 Feb 16;100(4):229-35. doi: 10.1024/1661-8157/a00442.
Amblyopia is a condition of decreased monocular or binocular visual acuity caused by form deprivation or abnormal binocular interaction. Amblyopia is the most common cause of monocular vision loss in children with a prevalence of 2 to 5%. During the last decade, several prospective randomized studies have influenced our clinical management. Based on these studies, optimum refractive correction should be prescribed first. However, most patients will need additional occlusion therapy which is still considered the «gold standard» of amblyopia management. Now much lower doses have been shown to be effective. In moderate amblyopia, penalization with atropine is as effective as patching. New treatment modalities including perceptual learning, pharmacotherapy with levodopa and citicholine or transcranial magnetic stimulation have not yet been widely accepted.
弱视是一种由形觉剥夺或双眼异常相互作用引起的单眼或双眼视力下降的病症。弱视是儿童单眼视力丧失的最常见原因,患病率为2%至5%。在过去十年中,多项前瞻性随机研究影响了我们的临床管理。基于这些研究,应首先开具最佳的屈光矫正处方。然而,大多数患者需要额外的遮盖疗法,这仍然被认为是弱视治疗的“金标准”。现在已证明低得多的剂量也有效。在中度弱视中,阿托品压抑疗法与遮盖疗法效果相当。包括感知学习、左旋多巴和胞磷胆碱药物治疗或经颅磁刺激在内的新治疗方法尚未被广泛接受。