Department of Diagnostic Radiology and Multi-dimension Biomedical Imaging & Information Laboratory in Research Park, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Radiology. 2011 Apr;259(1):257-62. doi: 10.1148/radiol.11100978. Epub 2011 Feb 17.
To compare image quality obtained in phantoms with virtual monochromatic spectral (VMS) imaging with that obtained with conventional 120-kVp computed tomography (CT) for a given radiation dose.
Three syringes were filled with a diluted contrast medium (each syringe contained a contrast medium with a different iodine concentration [5, 10, or 15 mg of iodine per milliliter]), and a fourth syringe was filled with water. These syringes were placed in a torso phantom meant to simulate the standard human physique. The phantom was examined with a CT system and use of the fast kilovoltage switching (80 and 140 kVp) and conventional (120 kVp) modes. Image noise and contrast-to-noise (CNR) ratio were analyzed on VMS images and 120-kVp CT images.
Image noise on VMS images in the range of 67-72 keV was significantly lower than that on the 120-kVp CT images (P < .014). Image noise was lowest at 69 keV and was 12% lower when compared with that on 120-kVp CT images. CNR on the VMS images was highest at 68 keV. CNR on the VMS images obtained at 68 keV in the syringes filled with diluted contrast material (5, 10, and 15 mg of iodine per milliliter) was 28%, 31%, and 30% higher, respectively, compared with that on the 120-kVp CT images (P < .001).
VMS imaging at approximately 70 keV yielded lower image noise and higher CNR than did 120-kVp CT for a given radiation dose. VMS imaging has the potential to replace 120-kVp CT as the standard CT imaging modality, since optimal VMS imaging may be expected to yield improved image quality in a patient with standard body habitus.
比较虚拟单能量光谱(VMS)成像与常规 120kVp 计算机断层扫描(CT)在给定辐射剂量下获得的图像质量。
三个注射器中分别注入稀释的对比剂(每个注射器中含有不同碘浓度的对比剂[每毫升 5、10 或 15 毫克碘]),第四个注射器中注入水。这些注射器放置在一个模拟标准人体体型的体模中。使用 CT 系统和快速千伏切换(80 和 140kVp)和常规(120kVp)模式对体模进行检查。在 VMS 图像和 120kVp CT 图像上分析图像噪声和对比噪声比(CNR)。
67-72keV 范围内 VMS 图像的图像噪声明显低于 120kVp CT 图像(P<0.014)。在 69keV 时图像噪声最低,与 120kVp CT 图像相比降低了 12%。在 VMS 图像上,CNR 在 68keV 时最高。在充满稀释对比剂(每毫升 5、10 和 15 毫克碘)的注射器中,VMS 图像在 68keV 时的 CNR 分别比 120kVp CT 图像高 28%、31%和 30%(P<0.001)。
在给定辐射剂量下,VMS 成像在约 70keV 时产生的图像噪声低于 120kVp CT,CNR 高于 120kVp CT。VMS 成像有可能取代 120kVp CT 作为标准 CT 成像方式,因为预计最佳 VMS 成像可能会在具有标准体型的患者中产生改善的图像质量。