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通过遗传学、基因组学和分子生物学的进步来改善人类法医学。

Improving human forensics through advances in genetics, genomics and molecular biology.

机构信息

Department of Forensic Molecular Biology, Erasmus MC University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands.

出版信息

Nat Rev Genet. 2011 Mar;12(3):179-92. doi: 10.1038/nrg2952.

Abstract

Forensic DNA profiling currently allows the identification of persons already known to investigating authorities. Recent advances have produced new types of genetic markers with the potential to overcome some important limitations of current DNA profiling methods. Moreover, other developments are enabling completely new kinds of forensically relevant information to be extracted from biological samples. These include new molecular approaches for finding individuals previously unknown to investigators, and new molecular methods to support links between forensic sample donors and criminal acts. Such advances in genetics, genomics and molecular biology are likely to improve human forensic case work in the near future.

摘要

法医 DNA 分析目前可以识别已经为调查机关所知的人员。最近的进展产生了新类型的遗传标记,有可能克服当前 DNA 分析方法的一些重要限制。此外,其他方面的发展使人们能够从生物样本中提取全新类型的与法医有关的信息。这些信息包括寻找调查人员先前未知的个人的新分子方法,以及支持法医样本捐赠者与犯罪行为之间联系的新分子方法。遗传学、基因组学和分子生物学方面的这些进展可能会在不久的将来改善人类法医案件工作。

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