Department of Nephrology, Ankara Education and Research Hospital, Ankara, Turkey.
Ren Fail. 2011;33(2):244-5. doi: 10.3109/0886022X.2010.541577.
Thrombotic thrombocytopenic purpura (TTP)/hemolytic uremic syndrome (HUS) is characterized with fever, purpura, anemia due to microangiopathic hemolysis, thrombocytopenia, kidney damage, and neurologic symptoms. The development of TTP/HUS during the course of inflammatory bowel diseases was rarely reported. However, coexistence of TTP/HUS and Crohn's disease in the same patient has not been reported previously. We herein present a case of TTP/HUS who presented with Crohn's disease. He responded to cyclosporine treatment.
血栓性血小板减少性紫癜(TTP)/溶血尿毒综合征(HUS)的特征为发热、紫癜、微血管病性溶血性贫血导致的贫血、血小板减少、肾损伤和神经症状。炎症性肠病过程中发生 TTP/HUS 的情况很少见。然而,TTP/HUS 与克罗恩病同时存在于同一患者的情况以前尚未报道。我们在此报告一例以克罗恩病表现的 TTP/HUS 患者。他对环孢素治疗有反应。