Shoklo Malaria Research Unit, Mae Sot, Tak, Thailand.
BJOG. 2011 May;118(6):671-8. doi: 10.1111/j.1471-0528.2010.02880.x. Epub 2011 Feb 18.
Recommendations for interventions to control malaria in pregnancy are often based on studies using birthweight as the primary endpoint. Differences in birthweight may be attributable partly to methodological difficulties. We performed a structured search of the literature using 'malaria', 'pregnancy' and 'birth weight' as search terms. Of the clinical trials reporting birthweight, only 33% (14/43) gave information about the timing of the measurement and details on the scales used. Seventy seven per cent explained how gestational age was estimated. We propose a standardised method for the measurement and reporting of birthweight in future studies.
控制孕妇疟疾的干预措施建议通常基于以出生体重为主要终点的研究。出生体重的差异可能部分归因于方法学上的困难。我们使用“疟疾”、“妊娠”和“出生体重”作为搜索词,对文献进行了结构化搜索。在报告出生体重的临床试验中,只有 33%(43 项中的 14 项)提供了关于测量时间和使用的秤的详细信息。77%的试验解释了如何估计胎龄。我们建议在未来的研究中采用一种标准化的方法来测量和报告出生体重。