Department of Dermatology, Hospital Universitario Central de Asturias, Oviedo, Spain.
Australas J Dermatol. 2011 Feb;52(1):56-8. doi: 10.1111/j.1440-0960.2010.00675.x. Epub 2010 Aug 16.
Cetuximab, an epidermal growth factor receptor inhibitor, is a chemotherapeutical agent featuring well-known adverse dermatological effects related to tumour-response prognosis. In psoriasis, the epidermal growth factor receptor is overexpressed; hence, the expectation would be that an epidermal growth factor receptor inhibitor could improve psoriatic lesions. We report a case of psoriasis induced by cetuximab, which was a surprising adverse effect.
西妥昔单抗，一种表皮生长因子受体抑制剂，是一种化疗药物，具有与肿瘤反应预后相关的众所周知的不良皮肤效应。在银屑病中，表皮生长因子受体过度表达；因此，人们期望表皮生长因子受体抑制剂可以改善银屑病病变。我们报告了一例由西妥昔单抗引起的银屑病，这是一种令人惊讶的不良反应。
