Angeretti A, Ferrara B, Biglino A, Merlino C, Negro Ponzi A
Institute of Microbiology, Turin, Italy.
G Batteriol Virol Immunol. 1990 Jan-Dec;83(1-12):138-42.
Serum anti-HBc IgA antibodies can be demonstrated in acute hepatitis B patients. At first, they are mainly polymeric (p-IgA), whereas monomeric IgA (m-IgA) become detectable 3 months later. In most cases, anti-HBc IgA cannot be demonstrated after 6-12 months. From a diagnostic point of view, specific p-IgA can be regarded as a marker of active infection but, compared to IgM, their demonstration is more difficult.
急性乙型肝炎患者血清中可检测到抗 - HBc IgA抗体。起初，它们主要是聚合型（p - IgA），而单体IgA（m - IgA）在3个月后可被检测到。在大多数情况下，6 - 12个月后无法检测到抗 - HBc IgA。从诊断角度来看，特异性p - IgA可被视为活动性感染的标志物，但与IgM相比，其检测更为困难。
