Siddiqui Saima Aziz, Tariq Gulfishan, Soomro Nargis, Sheikh Aneela, Shabih-ul-Hasnain Farah, Memon Kanwal Aftab
Department of Obstetrics and Gynaecology, Unit II, Dow University of Health Sciences and Civil Hospital, Karachi.
J Coll Physicians Surg Pak. 2011 Feb;21(2):79-83.
To compare perinatal outcome and near-miss morbidities between placenta previa versus abruptio placentae in patients of antepartum haemorrhage (APH).
Cross-sectional, analytical study.
Gynaecology Unit II, Civil Hospital, Karachi, from August 2007 to July 2009.
Patients with APH diagnosed as placenta previa and abruptio placentae who delivered after 24 weeks of pregnancy were selected from labour room. Outcome measures were birth weight, neonatal intensive care admission, stillbirth, perinatal mortality rates, near-miss, surgical intensive care admission, postpartum haemorrhage, hysterectomy, massive transfusion, renal failure, coagulopathy and maternal death. Stillbirth was defined as a fetus weighing≥500 gm showing no sign of life after birth. Near-miss was defined as severe organ dysfunction which if not treated appropriately, could result in death. Descriptive statistics were calculated and chi-square was applied with significance level<0.05.
Stillbirths and perinatal mortality rates were significantly higher in abruptio placentae, 52.97% versus 18.18% and 534/1000 versus 230/1000 (p<0.01). Near-miss cases were also significantly higher in abruptio placentae, 22.27% verus 11.18% (p<0.01). Hypovolemic shock and coagulation failure were also significantly higher in abruptio placentae (p<0.05).
Abruptio placentae carry significantly higher perinatal mortality and near-miss morbidity than placenta previa.
比较前置胎盘与胎盘早剥所致产前出血(APH)患者的围产期结局及接近死亡的发病率。
横断面分析研究。
2007年8月至2009年7月,卡拉奇市民医院妇科二科。
从产房选取妊娠24周后分娩的被诊断为前置胎盘和胎盘早剥的产前出血患者。观察指标包括出生体重、新生儿重症监护病房收治情况、死产、围产儿死亡率、接近死亡情况、外科重症监护病房收治情况、产后出血、子宫切除术、大量输血、肾衰竭、凝血功能障碍及孕产妇死亡。死产定义为出生体重≥500克且出生后无生命迹象的胎儿。接近死亡定义为严重器官功能障碍,若未得到适当治疗可能导致死亡。计算描述性统计量,并应用卡方检验,显著性水平<0.05。
胎盘早剥组的死产率和围产儿死亡率显著更高,分别为52.97%对18.18%,以及534/1000对230/1000(p<0.01)。胎盘早剥组的接近死亡病例也显著更多,为22.27%对11.18%(p<0.01)。胎盘早剥组的低血容量性休克和凝血功能衰竭也显著更高(p<0.05)。
胎盘早剥所致围产儿死亡率和接近死亡的发病率显著高于前置胎盘。