肺癌患者支气管肺泡灌洗液：应用蛋白质组学技术绘制未知水域图。
Bronchoalveolar lavage fluid of lung cancer patients: mapping the uncharted waters using proteomics technology.
出版信息
Lung Cancer. 2011 Apr;72(1):136-8. doi: 10.1016/j.lungcan.2011.01.015. Epub 2011 Feb 18.
Abstract
The search for proteome-level markers of non-small cell lung cancer (NSCLC) has been mainly limited to serum or cell line screening approaches up to this point. We would like to demonstrate by this proof-of-principle study investigating bronchoalveolar lavage fluid samples from a cohort of NSCLC and control patients, that this readily available biofluid might be a more suitable source for discovering clinically usable NSCLC biomarkers.
摘要
到目前为止，针对非小细胞肺癌（NSCLC）的蛋白质组水平标志物的研究主要局限于血清或细胞系筛选方法。通过对一组 NSCLC 患者和对照患者的支气管肺泡灌洗液样本进行的这项原理验证研究，我们希望证明这种易于获得的生物液可能是发现具有临床应用价值的 NSCLC 生物标志物的更合适来源。
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