Department of Psychology, University of Vermont, Burlington, VT 05405-0134, USA.
J Psychosom Res. 2011 Mar;70(3):258-66. doi: 10.1016/j.jpsychores.2010.07.011. Epub 2010 Sep 21.
The present investigation sought to examine the simultaneous effects of anxiety sensitivity and pain-related anxiety on fear and anxious responding to a 10% carbon dioxide enriched air challenge.
Participants included 247 adults (53% women; mean age=21.91 years, S.D.=8.41) recruited from the community. At the laboratory, participants were administered a structured clinical interview, completed a battery of self-report measures, and underwent a 10% carbon dioxide enriched air challenge.
Both anxiety sensitivity and pain-related anxiety were significantly and uniquely predictive of post-challenge panic attacks, total post-challenge panic attack symptoms, and intensity of cognitive panic attack symptoms. Anxiety sensitivity, but not pain-related anxiety, also was predictive of post-challenge physical panic symptoms. The observed significant effects for both anxiety sensitivity and pain-related anxiety were evident above and beyond the variance accounted for by gender, age, current level of nonspecific bodily pain, and negative affectivity. Neither anxiety sensitivity nor pain-related anxiety was significantly predictive of change in anxiety focused on bodily sensations or heart rate.
Results suggest that anxiety sensitivity and pain-related anxiety, although related to one another, may be independently important variables underlying fear reactivity to bodily sensations.
本研究旨在考察焦虑敏感和与疼痛相关的焦虑对 10%二氧化碳富集空气挑战时的恐惧和焦虑反应的同时影响。
参与者包括 247 名来自社区的成年人（53%为女性；平均年龄=21.91 岁，标准差=8.41）。在实验室中，参与者接受了结构化临床访谈，完成了一系列自我报告量表，并接受了 10%二氧化碳富集空气挑战。
焦虑敏感和与疼痛相关的焦虑均显著且独特地预测了挑战后的惊恐发作、总惊恐发作症状和认知惊恐发作症状的强度。焦虑敏感，而不是与疼痛相关的焦虑，也预测了挑战后的身体惊恐症状。焦虑敏感和与疼痛相关的焦虑的观察到的显著影响在性别、年龄、当前非特异性身体疼痛程度和负性情感之外，还存在显著影响。焦虑敏感和与疼痛相关的焦虑均不能显著预测对身体感觉或心率的焦虑的变化。
结果表明，焦虑敏感和与疼痛相关的焦虑虽然相互关联，但可能是对身体感觉的恐惧反应的独立重要变量。
