University of Vermont, Department of Psychology, John Dewey Hall, Burlington, VT 05405-0134, United States.
J Anxiety Disord. 2010 Jan;24(1):16-22. doi: 10.1016/j.janxdis.2009.07.025.
The current study investigated anxiety sensitivity, distress tolerance (Simons & Gaher, 2005), and discomfort intolerance (Schmidt, Richey, Cromer, & Buckner, 2007) in relation to panic-relevant responding (i.e., panic attack symptoms and panic-relevant cognitions) to a 10% carbon dioxide enriched air challenge. Participants were 216 adults (52.6% female; M(age)=22.4, SD=9.0). A series of hierarchical multiple regressions was conducted with covariates of negative affectivity and past year panic attack history in step one of the model, and anxiety sensitivity, discomfort intolerance, and distress tolerance entered simultaneously into step two. Results indicated that anxiety sensitivity, but not distress tolerance or discomfort intolerance, was significantly incrementally predictive of physical panic attack symptoms and cognitive panic attack symptoms. Additionally, anxiety sensitivity was significantly predictive of variance in panic attack status during the challenge. These findings emphasize the important, unique role of anxiety sensitivity in predicting risk for panic psychopathology, even when considered in the context of other theoretically relevant emotion vulnerability variables.
本研究调查了焦虑敏感性、痛苦耐受力（Simons & Gaher，2005）和不适耐受力（Schmidt、Richey、Cromer 和 Buckner，2007）与对 10%二氧化碳富集空气挑战的恐慌相关反应（即恐慌发作症状和与恐慌相关的认知）之间的关系。参与者为 216 名成年人（52.6%为女性；M（年龄）=22.4，SD=9.0）。在模型的第一步中，对负性情感和过去一年的恐慌发作史进行了一系列层次多重回归，然后同时将焦虑敏感性、不适耐受力和痛苦耐受力纳入第二步。结果表明，焦虑敏感性而非痛苦耐受力或不适耐受力显著增量预测了身体性恐慌发作症状和认知性恐慌发作症状。此外，焦虑敏感性显著预测了挑战期间恐慌发作状态的差异。这些发现强调了焦虑敏感性在预测恐慌性精神病理学风险方面的重要、独特作用，即使在考虑到其他理论上相关的情绪脆弱性变量的情况下也是如此。
