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[氩激光小梁成形术在开角型青光眼治疗中的作用:7年回顾性经验]

[Role of argon laser trabeculoplasty in the treatment of open-angle glaucoma: a 7-year retrospective experience].

作者信息

Detry-Morel M, Kallay O

机构信息

Service d'Ophthalmologie, Clinique Universitaire St. Luc, Bruxelles.

出版信息

Bull Soc Belge Ophtalmol. 1990;239:119-29.

PMID:2133528
Abstract

We present a retrospective study of 534 Argon laser trabeculoplasty which we realized from January 1983 to July 1990 on 356 primary open-angle glaucoma and secondary open-angle glaucoma patients. Follow-up is ranging from 3 months to 7 years. Photocoagulation was limited to 180 degrees trabecular surface in 300 cases and were completed to 360 degrees in the 234 other eyes. We observed an overall cumulated success rate of 87% at 6 months, which decreased slowly further to reach 32.6% at 6 years. Before laser, the mean intra-ocular pressure was 25 mmHg, this value decreased "a maxima" after 18 months (6.3 mmHg) and slowly increased afterwards but was still significant at 6 years. Some parameters may be of better prognosis: an age equal or older than 65 years, pigmentary dispersion syndrome and pseudo-exfoliative glaucoma. Laser trabeculoplasty associated with hypotensive drugs are an efficient and innocuous technic for controlling open-angle glaucoma; however, after a 30 months mean period, we observe a decrease of their efficiency.

摘要

我们对1983年1月至1990年7月间对356例原发性开角型青光眼和继发性开角型青光眼患者实施的534次氩激光小梁成形术进行了回顾性研究。随访时间为3个月至7年。300例患者的光凝范围限于小梁表面180度,另外234只眼则完成了360度光凝。我们观察到6个月时的总体累积成功率为87%,此后逐渐缓慢下降,6年时降至32.6%。激光治疗前,平均眼压为25 mmHg,18个月后降至最低值(6.3 mmHg),随后缓慢上升,但6年时仍有显著下降。一些参数可能提示预后较好:年龄等于或大于65岁、色素性分散综合征和假性剥脱性青光眼。氩激光小梁成形术联合降压药物是控制开角型青光眼的一种有效且无害的技术;然而,平均30个月后,我们观察到其疗效有所下降。

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