基于寡核苷酸的金属离子荧光检测。
Oligonucleotide-based luminescent detection of metal ions.
机构信息
Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, China.
出版信息
Chem Asian J. 2011 Apr 4;6(4):986-1003. doi: 10.1002/asia.201000870. Epub 2011 Feb 18.
PMID:21337527
Abstract
Metal ions are prevalent in biological systems and are critically involved in essential life processes. However, excess concentrations of metals can pose a serious danger to living organisms. Oligonucleotides represent a versatile sensing platform for the detection of various molecular entities including metal ions. This review summarizes the recent advances in the development of oligonucleotide-based luminescent detection methods for metal ions.
摘要
金属离子在生物系统中普遍存在，并在重要的生命过程中起着至关重要的作用。然而，过量的金属浓度会对生物体构成严重威胁。寡核苷酸是一种多功能的传感平台，可用于检测各种分子实体，包括金属离子。本综述总结了基于寡核苷酸的荧光检测方法在金属离子检测方面的最新进展。
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