State Key Laboratory of Physical Chemistry of Solid Surfaces, Department of Chemical Biology, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.
Chem Commun (Camb). 2011 Sep 7;47(33):9312-4. doi: 10.1039/c1cc12290h. Epub 2011 May 31.
We propose the use of DNAzyme as a crosslinker of hydrogel to develop a catalytic platform for the sensing of metal ions. The DNAzyme crosslinked hydrogel can undergo gel-sol transition in response to Cu(2+) ions, which enables sensitive visual detection of Cu(2+) by observing the release of pre-trapped AuNPs.
我们提出使用 DNA 酶作为水凝胶的交联剂,开发用于金属离子传感的催化平台。DNA 酶交联水凝胶可以响应 Cu(2+)离子发生凝胶-溶胶转变,通过观察预先捕获的 AuNPs 的释放来实现对 Cu(2+)的灵敏可视化检测。