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剖宫产术后由人型支原体引起的血肿和脓肿形成。

Hematoma and abscess formation caused by Mycoplasma hominis following cesarean section.

机构信息

Department of Obstetrics and Gynecology, Kyoto Prefectural Yosanoumi Hospital, Kyoto, Japan;

出版信息

Int J Womens Health. 2011 Jan 17;3:15-8. doi: 10.2147/IJWH.S16703.

Abstract

Mycoplasma species cannot be identified by routine bacteriological culture methods and are resistant to common antimicrobial agents. Mycoplasma hominis usually colonizes the lower urogenital tract and causes pyelonephritis, pelvic inflammatory disease, chorioamnionitis, rupture of fetal membranes, preterm labor, postpartum fever, postabortal fever, and neonatal infection. This organism is highly prevalent in cervicovaginal cultures of sexually active women. M. hominis, M. genitalis, Ureaplasma urealyticum, and U. parvum may invade and infect placental and fetal tissues, leading to adverse pregnancy outcomes. M. hominis occasionally causes nongenitourinary infection of the blood, wounds, central nervous system, joints, or respiratory tract. We present a case of a 27-year-old woman who developed abdominal wound hematoma and abscess after cesarean section. The wound was drained, but her high fever persisted, in spite of antibiotic treatment using flomoxef sodium and imipenem·cilastatin sodium. Because the exudate exhibited M. hominis growth in an anaerobic environment, we administered the quinolone ciprofloxacin. This therapy resolved her fever, and her white blood cell count and C-reactive protein level diminished to the normal ranges. To our knowledge, there are four published articles regarding the isolation of M. hominis from postcesarean incisions. Based on the current study and the literature, infection by this pathogen may cause hematoma formation with or without abscess after cesarean section or in immunosuppressed postoperative patients. In such cases, physicians may need to suspect Mycoplasma infection and initiate appropriate antibacterial treatment as soon as possible in order to avoid persistent fever.

摘要

支原体属不能通过常规细菌培养方法鉴定,且对常见抗菌药物具有耐药性。人型支原体通常定植于下泌尿生殖道,引起肾盂肾炎、盆腔炎、绒毛膜羊膜炎、胎膜早破、早产、产后发热、流产后发热和新生儿感染。该病原体在有性生活的女性宫颈阴道培养中高度流行。人型支原体、生殖支原体、解脲脲原体和微小脲原体可能侵袭和感染胎盘和胎儿组织,导致不良妊娠结局。人型支原体偶尔引起血液、伤口、中枢神经系统、关节或呼吸道的非泌尿生殖系统感染。我们报告了 1 例 27 岁女性在剖宫产术后发生腹部伤口血肿和脓肿。虽然使用头孢呋辛钠和亚胺培南西司他丁钠进行了抗生素治疗,但她的高热仍持续存在。由于渗出物在厌氧环境中显示出人型支原体的生长,我们给予了喹诺酮类环丙沙星。该治疗方案使她的发热得到缓解,白细胞计数和 C 反应蛋白水平降至正常范围。据我们所知,有 4 篇关于人型支原体从剖宫产切口分离的文献报道。基于本研究和文献,该病原体感染可能导致剖宫产术后或免疫抑制术后患者出现血肿形成,伴或不伴有脓肿。在这种情况下,医生可能需要怀疑支原体感染,并尽快启动适当的抗菌治疗,以避免持续发热。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1be7/3039004/a255fb5fd727/ijwh-3-015f1.jpg

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