Mori Nobuaki, Takigawa Aya, Kagawa Narito, Kenri Tsuyoshi, Yoshida Shinji, Shibayama Keigo, Aoki Yasuko
Department of General Internal Medicine, National Hospital Organization Tokyo Medical Center, 2-5-1 Higashigaoka, Meguro-ku, Tokyo 152-8902, Japan.
Department of Gynecology Medicine, National Hospital Organization Tokyo Medical Center, 2-5-1 Higashigaoka, Meguro-ku, Tokyo 152-8902, Japan.
JMM Case Rep. 2016 Aug 30;3(4):e005059. doi: 10.1099/jmmcr.0.005059. eCollection 2016 Aug.
is associated with genito-urinary tract infection and adverse pregnancy outcomes. However, whether the species is a true pathogen or part of the genito-urinary tracts natural flora remains unclear.
A 41-year-old pregnant woman was admitted to our hospital at 38 weeks and 5 days of gestation owing to premature rupture of the membranes. The patient delivered by caesarean section. Subsequently, the patient complained of lower abdominal pain and had persistent fever. Enhanced computed tomography revealed pelvic abscesses. Gram staining of pus from the abscess and vaginal secretions indicated presence of polymorphonuclear leucocytes but no pathogens. Cultures on blood agar showed growth of pinpoint-sized colonies in an anaerobic environment within 48 h. Although administration of carbapenem and metronidazole was ineffective and we could not fully drain the abscess, administration of clindamycin led to clinical improvement. The isolates 16S rRNA gene and gene sequences exhibited identity with those of
Physicians should consider in cases of pelvic abscesses where Gram staining yields negative results, small colonies are isolated from the abscess and treatment with β-lactam antibiotics is ineffective.
与泌尿生殖道感染及不良妊娠结局相关。然而,该菌种是真正的病原体还是泌尿生殖道自然菌群的一部分仍不清楚。
一名41岁孕妇因胎膜早破于妊娠38周零5天时入院。患者行剖宫产分娩。随后,患者主诉下腹部疼痛并持续发热。增强计算机断层扫描显示盆腔脓肿。脓肿脓液及阴道分泌物的革兰氏染色显示有多形核白细胞但无病原体。血琼脂培养显示在厌氧环境中48小时内有针尖大小的菌落生长。尽管使用碳青霉烯类和甲硝唑无效且脓肿无法完全引流,但使用克林霉素后临床症状改善。分离株的16S rRNA基因和 基因序列与 的基因序列相同。
对于盆腔脓肿病例,若革兰氏染色结果为阴性、从脓肿中分离出小菌落且β-内酰胺类抗生素治疗无效,医生应考虑 。