Sámano Reyna, Morales Rosa María, Flores-García Adriana, Lira Josefina, Isoard Fernando, de Santiago Soledad, Casanueva Esther
Instituto Nacional de Perinatología, DF, México.
Salud Publica Mex. 2011 Jan-Feb;53(1):2-10. doi: 10.1590/s0036-36342011000100002.
To analyze the pattern of bone mineral density (BMD), serum concentrations of estradiol and calcium levels, dietary calcium, body mass index (BMI), and lactation in adolescents and adult women at 15, 90, and 365 postpartum days (ppd).
A prospective cohort study was conducted of 33 adolescents and 39 adult women. Anthropometric and dietetic evaluations were performed, as well as evaluations of bone mineral density in L2-L4 and femur neck. Estradiol concentrations and calcium serum levels were determined.
L2-L4 BMD increased by 16% in adolescents, and 3% in adult women from day 15 to 365 ppd. While age was associated with this change (β=13.779, EE=3.5, p=0.001), lactation was not (β=-0.705, EE=0.647, p=0.283). The adult women had a higher L2-L4 BMD at 15, 90, and 635 ppd (1.151 vs 0.978 g/cm², 1.195 vs 1.070 g/cm², 1.195 vs 1.123 g/cm², respectively) (p<0.003).
Adolescents' BMD increased three times more than that of adult women. For all women, BMD was dependent of age and independent of lactation.
分析青少年和成年女性在产后15天、90天和365天的骨矿物质密度（BMD）模式、雌二醇血清浓度和钙水平、膳食钙、体重指数（BMI）以及哺乳情况。
对33名青少年和39名成年女性进行了一项前瞻性队列研究。进行了人体测量和饮食评估，以及L2-L4和股骨颈的骨矿物质密度评估。测定了雌二醇浓度和血清钙水平。
从产后15天到365天，青少年的L2-L4骨密度增加了16%，成年女性增加了3%。虽然年龄与这种变化相关（β=13.779，标准误=3.5，p=0.001），但哺乳情况并非如此（β=-0.705，标准误=0.647，p=0.283）。成年女性在产后15天、90天和635天的L2-L4骨密度更高（分别为1.151 vs 0.978 g/cm²、1.195 vs 1.070 g/cm²、1.195 vs 1.123 g/cm²）（p<0.003）。
青少年的骨密度增加幅度是成年女性的三倍。对于所有女性来说，骨密度取决于年龄，与哺乳无关。
