Malpeli Agustina, Apezteguia María, Mansur José L, Armanini Alicia, Macías Couret Melisa, Villalobos Rosa, Kuzminczuk Marta, Gonzalez Horacio F
IDIP - Instituto de Desarrollo e Investigaciones Pediátricas "Prof. D. Fernando E. Viteri", Hospital de Niños de La Plata, (MS/CIC-PBA), La Plata, Argentina.
Arch Latinoam Nutr. 2012 Mar;62(1):30-6.
We determined the effect of calcium supplementation on bone mineral density (BMD) and bone mineral content (BMC) and identified predictors of bone mass changes in adolescent mothers 6 months postpartum. A prospective, analytical, clinical study was performed in adolescent mothers (< or = 19 years old; n = 37) from La Plata, Argentina. At 15 days postpartum, mothers were randomly assigned into one of two groups and started with calcium supplementation; one group received dairy products (932 mg Ca; n = 19) and the other calcium citrate tablets (1000 mg calcium/day; n = 18). Weight, height and dietary intake were measured and BMD was determined by DEXA at 15 days (baseline) and 6 months postpartum. BMC, total body BMD and BMD were assessed in lumbar spine, femoral neck, trochanter and total hip. Regression models were used to identify the relationship of total body BMD and BMC with independent variables (calcium supplementation, months of lactation, weight at 6 months, percent weight change, lean mass at 6 months, percent lean mass change, total calcium intake). Results showed that changes in BMD and BMC at the different sites were similar in both groups, and changes in percent body weight and total calcium intake were the main predictive factors. In conclusion, the effect of calcium was similar with either form of supplementation, i.e., dairy products or tablets, and changes in percent body weight and total calcium intake were predictors of total body BMD and BMC changes.
我们测定了补钙对骨矿物质密度（BMD）和骨矿物质含量（BMC）的影响，并确定了产后6个月的青春期母亲骨量变化的预测因素。对来自阿根廷拉普拉塔的青春期母亲（≤19岁；n = 37）进行了一项前瞻性、分析性临床研究。产后15天时，母亲们被随机分为两组之一并开始补钙；一组接受乳制品（932毫克钙；n = 19），另一组接受柠檬酸钙片（1000毫克钙/天；n = 18）。测量体重、身高和饮食摄入量，并在产后15天（基线）和6个月时通过双能X线吸收法（DEXA）测定BMD。在腰椎、股骨颈、大转子和全髋部评估BMC、全身BMD和BMD。使用回归模型确定全身BMD和BMC与自变量（补钙、哺乳月数、6个月时的体重、体重变化百分比、6个月时的瘦体重、瘦体重变化百分比、总钙摄入量）之间的关系。结果显示，两组不同部位的BMD和BMC变化相似，体重变化百分比和总钙摄入量变化是主要预测因素。总之，乳制品或片剂这两种补钙形式的效果相似，体重变化百分比和总钙摄入量变化是全身BMD和BMC变化的预测因素。
