Lopes Neto Jose Mauricio, Severo Leonardo Muller, Mendes Rinaldo Poncio, Weber Silke Anna Thereza
Hospital das Clínicas, Faculdade de Medicina de Botucatu.
Braz J Otorhinolaryngol. 2011 Jan-Feb;77(1):39-43. doi: 10.1590/s1808-86942011000100007.
Paracoccidioidomycosis (PCM) is a systemic disease that in its aftermath form is characterized by clinical manifestations related to anatomic or functional sequelae of organs and systems affected during the period of state. To describe the anatomical and functional sequelae in patients with treated laryngeal PCM. Retrospective study. We reviewed the charts from of 49 male patients, aged between 30 to 60 years, diagnosed with laryngeal PCM during the period of 1999 to 2004. In all patients the diagnosis of PCM was confirmed by demonstration of the fungus in sputum, cytological or histopathological examination and being followed up by the Infectious and Parasitic Diseases Department. The vocal folds were the most affected laryngeal structure, being affected in 67% of the patients. The epiglottis and the aryepiglottic folds were affected in 55% and 53% of the cases, respectively. Vestibular folds were changed in 46% of the patients. In 40% of the cases there were changes in the arytenoids. During phonation, 28% of the patients showed limited movement of the vocal folds, unilateral vocal fold paralysis was found in 4%. 24% of the cases had glottic lumen reduction and 4% showed glottic stenosis, 2% needed tracheostomy. Sequela lesions of the laryngeal PCM are extensive and cause functional limitations in most cases.
副球孢子菌病(PCM)是一种全身性疾病,其后期形式的特征是与患病期间受影响的器官和系统的解剖或功能后遗症相关的临床表现。描述经治疗的喉PCM患者的解剖和功能后遗症。回顾性研究。我们查阅了1999年至2004年期间诊断为喉PCM的49例30至60岁男性患者的病历。所有患者的PCM诊断均通过痰液中真菌的检测、细胞学或组织病理学检查得到证实,并由感染与寄生虫病科进行随访。声带是受影响最严重的喉部结构,67%的患者受其影响。会厌和声襞分别在55%和53%的病例中受到影响。46%的患者前庭襞发生改变。40%的病例杓状软骨有变化。发声时,28%的患者声带运动受限,4%发现单侧声带麻痹。24%的病例声门腔缩小,4%表现为声门狭窄,2%需要气管切开术。喉PCM的后遗症病变广泛,大多数情况下会导致功能受限。