Academic Medical Centre, Department of Vascular Medicine, F4-276, Meibergdreef 9, 1105, AZ, Amsterdam, The Netherlands.
J Thromb Thrombolysis. 2011 Apr;31(3):275-81. doi: 10.1007/s11239-011-0572-y.
Thrombophilia can be identified in about half of all patients presenting with VTE. Testing has increased tremendously for various indications, but whether the results of such tests help in the clinical management of patients has not been settled. I use evidence from observational studies to conclude that testing for hereditary thrombophilia generally does not alter the clinical management of patients with VTE, with occasional exceptions for women at fertile age. Because testing for thrombophilia only serves limited purpose this should not be performed on a routine basis.
约一半出现 VTE 的患者可检出血栓形成倾向。出于各种适应证，检测数量极大增加，但此类检测结果是否有助于患者的临床管理尚未确定。我利用观察性研究证据得出结论，一般而言，遗传性血栓形成倾向检测不会改变 VTE 患者的临床管理，除了生育年龄的女性有一些例外情况。由于血栓形成倾向检测仅具有有限的作用，因此不应常规进行。
