Cuervas-Mons M, Morte L, Junquera C, Ramón y Cajal S
Department of Cellular Biology, University College Soria, Valladolid University, Spain.
Histol Histopathol. 1990 Apr;5(2):193-8.
An histochemical research on cholinergic and noradrenergic fibres of the adventitia layer and of the myenteric plexus of the terminal ileum from rats with streptozotocin-induced diabetes, after 20 weeks of evolution of the illness, was carried out to study changes in the innervation of the gut. The cholinergic nerves, revealed through their acetylcholinesterase activity, did not present alterations, but an evident reduction in number of the noradrenergic nerves and swollen intensely fluorescent varicosities, were observed, both in the perivascular and myenteric plexus of terminal ileum from diabetic animals.
对链脲佐菌素诱导糖尿病大鼠病程20周后回肠末端外膜层和肌间神经丛的胆碱能和去甲肾上腺素能纤维进行了组织化学研究，以探讨肠道神经支配的变化。通过乙酰胆碱酯酶活性显示的胆碱能神经未出现改变，但在糖尿病动物回肠末端的血管周围和肌间神经丛中，观察到去甲肾上腺素能神经数量明显减少以及强烈荧光肿胀的曲张体。
