Khlopov N A, Kochkina L S, Sluchanko E I
Arkh Anat Gistol Embriol. 1991 Jan;100(1):19-24.
In the experiment performed on 60 mongrel dogs the effect of intravascular laser radiation of blood (ILRB) to adrenergic and cholinergic fibers of the small intestine has been studied at treatment of experimental generalized suppurative peritonitis. At treatment of the experimental peritonitis by means of traditional method only one month after its termination a positive reaction to acetylcholinesterase (AChE) is noted, structural organization of cholinergic fibers corresponds to the norm, and density of their plexuses increases. Application of ILRB at treatment of the experimental peritonitis facilitates to increasing density of the cholinergic fibers already on the 21st day after termination of the treatment; their AChE increases essentially, their structural organization corresponds to the norm. In cytoplasm of neurons of the muscular-intestinal plexus a positive reaction to AChE is revealed; this demonstrates their increased functional activity. The small intestine adrenergic apparatus at peritonitis undergoes less manifested structural-chemical alterations. After termination of treatment by means of traditional methods it corresponds to the norm on the 7th day, and after ILBR treatment----on the 3d day. Thus, application of ILBR in treatment of the experimental peritonitis enhances the development of regenerative processes in adrenal and cholinergic structures of the small intestine, facilitates a more manifested demonstration of compensatory-reparative possibilities of the organism.
在对60只杂种狗进行的实验中,研究了血管内激光照射血液(ILRB)对实验性弥漫性化脓性腹膜炎治疗中小肠肾上腺素能和胆碱能纤维的影响。采用传统方法治疗实验性腹膜炎,仅在治疗结束后一个月可观察到对乙酰胆碱酯酶(AChE)的阳性反应,胆碱能纤维的结构组织符合正常标准,且其丛密度增加。在实验性腹膜炎治疗中应用ILRB,在治疗结束后第21天即可促进胆碱能纤维密度增加;其AChE显著增加,结构组织符合正常标准。在肌肠丛神经元的细胞质中发现了对AChE的阳性反应,这表明其功能活性增强。腹膜炎时小肠肾上腺素能装置的结构化学改变不太明显。采用传统方法治疗结束后第7天符合正常标准,而采用ILBR治疗后第3天符合正常标准。因此,在实验性腹膜炎治疗中应用ILBR可促进小肠肾上腺能和胆碱能结构再生过程的发展,有助于更明显地展现机体的代偿修复能力。