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[大鼠尿道狭窄致膀胱梗阻的胆碱能和肾上腺素能神经支配]

[Cholinergic and adrenergic innervation of the bladder obstructed by urethral stenosis in the rat].

作者信息

Canon E, Timmermans L G, Lenaerts M, Timmermans L M

出版信息

C R Seances Soc Biol Fil. 1986;180(3):394-405.

PMID:2946384
Abstract

In the obstructed bladder by urethral stenosis the morphometry studies show a decrease of the cholinergic and adrenergic intrinsic innervation in a different way according the tissue layer and the experimental delay. Adrenergic nerves are more affected than cholinergic ones but they recover more quickly. In the adventitia and the sub-mucosa first affected by the high pressures inside the bladder the density of the autonomous nerves decreases from the first week. The perivascular and muscular nervous fibers are less sensitive and the similar shape of their innervation histogram gives evidence of a tight bond between their adrenergic network. Beside their motor participation the adrenergic terminal fibers may play a role in the cellular trophicity of the muscle.

摘要

在因尿道狭窄导致膀胱梗阻的情况下,形态学测量研究表明,根据组织层和实验延迟的不同,胆碱能和肾上腺素能内在神经支配以不同方式减少。肾上腺素能神经比胆碱能神经受影响更大,但恢复得更快。在首先受到膀胱内高压影响的外膜和粘膜下层,自主神经的密度从第一周开始下降。血管周围和肌肉神经纤维较不敏感,其神经支配直方图的相似形状证明了它们的肾上腺素能网络之间存在紧密联系。除了运动参与外,肾上腺素能终末纤维可能在肌肉的细胞营养方面发挥作用。

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