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多发性骨髓瘤患者后路固定术后胸椎主动脉穿孔致椎弓根螺钉位置不良的迟发诊断:病例报告。

Late diagnosis of pedicle screw malplacement with perforation of the thoracic aorta after posterior stabilization in a patient with multiple myeloma: case report.

机构信息

Department of Orthopaedic Surgery, University Hospital Leipzig, Leipzig, Germany.

出版信息

Spine (Phila Pa 1976). 2011 Jun;36(13):E886-90. doi: 10.1097/BRS.0b013e318202e4d1.

Abstract

STUDY DESIGN

A case report.

OBJECTIVE

To demonstrate delayed diagnosis of screw malpositioning with perforation of the thoracic aorta after posterior stabilization of a Th7-vertebral collapse due to multiple myeloma. Relevant diagnostic and therapeutic strategies are outlined in the context of a rather unfortunate series of interventional events.

SUMMARY OF BACKGROUND DATA

Pedicle screw instrumentation has become a well-established standard in the surgical treatment of various disorders of the spinal column. Particularly at the upper-thoracic level, the close anatomic relationship of the spine to the aorta places it and other major structures at high risk. Although iatrogenic vascular injuries are rare, a few cases have been described.

METHODS

A 64-year-old female patient remarked progressive back pain after 2 years of uneventful recovery from a multilevel posterior stabilization by pedicle screw and rod instrumentation because of an osteolytic collapse of the Th7 vertebra. The subsequent computed tomographic scan demonstrated kyphotic deformity of the thoracic spine with transspinal and periaortic screw malplacement.

RESULTS

The revision strategy was an interdisciplinary single session two-phase operation. The primary phase included a left-sided thoracotomy, mobilization of the thoracic aorta, and posterior implant removal under vascular monitoring in right lateral position. The initially planned corporectomy of Th7 and subsequent vertebral body replacement by cage implantation via the anterior approach was dismissed because of critical tissue adhesions of the thoracic aorta to the anterior vertebral column. Finally, the thoracotomy was closed, the patient transferred into prone position and stabilized by a multilevel posterior reinstrumentation under fluoroscopy guidance.

CONCLUSION

Although the clinical course in malpositioned pedicle screw instrumentation may stay unremarkable, this case illustrates that in a proven injury to the thoracic aorta revision is mandatory to prevent further vascular damage. The appropriate strategy demands exact and provident planning using a preferably interdisciplinary approach.

摘要

研究设计

病例报告。

目的

展示多发性骨髓瘤导致 Th7 椎体塌陷后后路稳定后,胸主动脉穿透性螺钉错位的延迟诊断。在一系列不幸的介入事件背景下,概述了相关的诊断和治疗策略。

背景数据概要

椎弓根螺钉固定已成为脊柱多种疾病手术治疗的标准。特别是在上胸段,脊柱与主动脉的解剖关系密切,使它和其他主要结构处于高风险状态。虽然医源性血管损伤很少见,但也有少数病例报道。

方法

一名 64 岁女性患者在接受多节段后路椎弓根螺钉和棒固定器稳定治疗后 2 年,因 Th7 椎体溶骨性塌陷而无并发症恢复后出现进行性背痛。随后的 CT 扫描显示胸椎后凸畸形,脊柱和主动脉周围螺钉错位。

结果

修订策略是一个跨学科的单阶段两阶段手术。第一阶段包括左侧开胸术,在右侧侧卧位下进行血管监测,移动胸主动脉,以及取出后路植入物。最初计划通过前路进行 Th7 的椎体切除术和随后的 cage 植入椎体置换术,由于胸主动脉与前脊柱的严重组织粘连而被放弃。最后,关闭开胸术,患者转移到俯卧位,并在透视引导下进行多节段后路再固定。

结论

尽管在错位椎弓根螺钉固定术中,临床过程可能没有明显变化,但本例表明,在证实有胸主动脉损伤的情况下,必须进行修复以防止进一步的血管损伤。适当的策略需要使用尽可能跨学科的方法进行精确和有远见的规划。

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