Durham Veterans Affairs Medical Center, Durham, NC 27705, USA.
J Clin Sleep Med. 2011 Feb 15;7(1):57-68.
A significant portion of US military personnel are returning from deployment with trauma-related sleep disturbance, and disrupted sleep has been proposed as a mechanism for the development of medical conditions in those with posttraumatic stress disorder (PTSD). Although individuals with PTSD may realize improved sleep with either PTSD treatment or CBT for insomnia, many continue to experience residual sleep difficulties. Newly developed interventions designed to address nightmares are effective to this end, but often do not fully remove all aspects of PTSD-related sleep difficulties when used in isolation. A combined intervention involving both a nightmare-specific intervention and CBT for insomnia may lead to more marked reductions in PTSD-related sleep disturbances.
Twenty-two veterans meeting criteria for PTSD were enrolled in the study. A combined intervention comprised of CBT for insomnia and imagery rehearsal therapy was evaluated against a usual care comparison group.
Intent-to-treat analyses revealed medium to large treatment effect sizes for all sleep diary outcomes, and very large treatment effects for insomnia severity, sleep quality, and PTSD symptoms.
Findings demonstrate that an intervention targeting trauma-specific sleep disturbance produces large short-term effects, including substantial reductions in PTSD symptoms and insomnia severity. Future research should focus on the optimal approach to the treatment of comorbid PTSD and sleep disturbance in terms of sequencing, and should assure that sleep-focused interventions are available and acceptable to our younger veterans, who were more likely to drop out of treatment.
相当一部分美国军人在部署后会出现与创伤相关的睡眠障碍,而睡眠中断被认为是创伤后应激障碍(PTSD)患者出现医疗状况的一种机制。尽管 PTSD 患者可能会通过 PTSD 治疗或失眠认知行为疗法(CBT)改善睡眠,但许多人仍会持续出现睡眠困难的残留问题。为解决噩梦问题而新开发的干预措施在这方面是有效的,但在单独使用时,往往不能完全消除与 PTSD 相关的睡眠困难的所有方面。包含特定于噩梦的干预和失眠 CBT 的联合干预可能会导致 PTSD 相关睡眠障碍的显著减少。
22 名符合 PTSD 标准的退伍军人参与了这项研究。CBT 联合意象排练疗法被评估为常规护理对照组。
意向治疗分析显示,所有睡眠日记结果均具有中到大的治疗效果,而失眠严重程度、睡眠质量和 PTSD 症状的治疗效果非常大。
研究结果表明,针对创伤相关睡眠障碍的干预措施可产生短期的显著效果,包括 PTSD 症状和失眠严重程度的大幅降低。未来的研究应侧重于针对 PTSD 和睡眠障碍共病的治疗方法,包括治疗顺序,应确保有针对性的睡眠干预措施可供我们的年轻退伍军人使用,他们更有可能退出治疗。