Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, China.
Chem Commun (Camb). 2011 Apr 7;47(13):4016-8. doi: 10.1039/c0cc05804a. Epub 2011 Feb 23.
The catalytic asymmetric aza-Michael reaction of benzoyl hydrazine toward chalcones through the nonactivated amine moiety conjugated addition was facilitated by the developed N,N'-dioxide-Sc(OTf)(3) complex under mild conditions, affording the pharmacologically and synthetically useful products in moderate to high yields with up to 97% ee.
在温和条件下，通过开发的 N,N'-二氧化物-Sc(OTf)3 配合物，促进了苯甲酰肼对查尔酮的非活化胺部分共轭加成的催化不对称氮杂-Michael 反应，以中等至较高的产率（高达 97%ee）提供了具有药理和合成用途的有用产物。
