Shenoy Radha, Al-Belushi Habiba, Al-Ajmi Sadiqa, Al-Nabhani Susan Margaret, Ganguly Shyam Sunder, Bialasiewicz Alexander A
Department of Ophthalmology, Sultan Qaboos University College of Medicine, Muscat, Al-Khod, Oman.
Middle East Afr J Ophthalmol. 2008 Apr;15(2):51-6. doi: 10.4103/0974-9233.51992.
To report on the changes of latency and amplitudes of the pattern VEP in patients with uncontrolled diabetes mellitus II and I before and after panretinal laser treatment.
Single center hospital based comparative study.
One hundred eyes of patients with proliferative diabetic vitreoretinopathy, and HbA1C ≥ 10 percent were subjected to Pattern Visually Evoked Potentials (Medtronic keyopint system, Nicolet) prior to and 4 weeks after PRP. Results were compared to age-matched non-diabetic controls. Chi-Square test, and paired 't' test were used for statistical analysis.
Preoperative mean VEP amplitude was 8.35mV±3.71, and not significantly different to the control group (mean 10.51mV±3.34) (chi square test p=1). Mean preoperative P100 latency was 106.93±7.90ms and significantly different to the control group (103.21±7.65ms) (paired t-test p=0.001). After laser treatment, VEP amplitudes decreased in 48/100 eyes (mean total 5.11mV±2.4), and P100 latency increased in 75/100 eyes (mean total 110.47±7.35ms).
In this study, PRP was followed by a significant decrease in VEP amplitudes in 48 percent and increase in latency in 75 percent of eyes.
