Jiang Guoqian, Solbrig Harold R, Iberson-Hurst Dave, Kush Rebecca D, Chute Christopher G
Summit Transl Bioinform. 2010 Mar 1;2010:11-5.
Semantic interoperability among terminologies, data elements, and information models is fundamental and critical for sharing information from the scientific bench to the clinical bedside and back among systems. To meet this need, the vision for CDISC is to build a global, accessible electronic library, which enables precise and standardized data element definitions that can be used in applications and studies to improve biomedical research and its link with health care. As a pilot study, we propose a representation and harmonization framework for clinical study data elements and implement a prototype CDISC Shared Health and Research Electronic Library (CSHARE) using Semantic MediaWiki. We report the preliminary observations of how the components worked and the lessons learnt. In summary, the wiki provided a useful prototyping tool from a process standpoint.
术语、数据元素和信息模型之间的语义互操作性对于在系统之间从科学实验台到临床床边再返回的信息共享至关重要。为满足这一需求，CDISC的愿景是构建一个全球可访问的电子图书馆，它能够提供精确且标准化的数据元素定义，这些定义可用于各种应用和研究，以改善生物医学研究及其与医疗保健的联系。作为一项试点研究，我们提出了一个临床研究数据元素的表示与协调框架，并使用语义维基（Semantic MediaWiki）实现了一个CDISC共享健康与研究电子图书馆（CSHARE）原型。我们报告了关于各组件如何运行以及所吸取教训的初步观察结果。总之，从流程角度来看，维基提供了一个有用的原型制作工具。
