Department of Biopathological Science and Hygiene of Animal and Food Productions Faculty of Veterinary Medicine, University of Perugia, 4 S Costanzo Street, Postal Box 06126, Perugia, Italy.
Parasitol Res. 2011 Aug;109(2):505-8. doi: 10.1007/s00436-011-2293-8. Epub 2011 Feb 24.
A case of disseminated angiostrongylosis caused by Angiostrongylus vasorum in a dog living in Italy is here described. The dog was referred for severe respiratory distress and epileptic seizures; clinicopathological findings were consistent with severe pneumonia associated with right-sided heart failure and multifocal involvement of the brain. Bronchoalveolar fluid analysis identified a multitude of nematode larvae, identified as A. vasorum by conventional and biomolecular (PCR) methods. The major anatomo-histopathological lesions were chronic granulomatous pneumonia, a severe multifocal granulomatous myocarditis and multifocal mild vascular and inflammatory disease in the brain. A. vasorum should be included among the differentials of dogs with cardiovascular and neurologic disease.
本文描述了一例意大利犬感染血管圆线虫引起的血管圆线虫病。该犬因严重呼吸窘迫和癫痫发作而被转诊；临床病理检查结果与严重肺炎相关，伴有右侧心力衰竭和大脑多灶性受累。支气管肺泡液分析发现大量线虫幼虫，通过常规和生物分子（PCR）方法鉴定为血管圆线虫。主要的解剖病理学病变为慢性肉芽肿性肺炎、严重的多灶性肉芽肿性心肌炎以及大脑多灶性轻度血管和炎症性疾病。血管圆线虫应包括在患有心血管和神经疾病的犬的鉴别诊断中。
