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Serological detection of circulating Angiostrongylus vasorum antigen and specific antibodies in dogs from central and northern Italy.意大利中北部地区犬体内循环血管圆线虫抗原和特异性抗体的血清学检测。
Vet Parasitol. 2013 Feb 18;192(1-3):192-8. doi: 10.1016/j.vetpar.2012.10.016. Epub 2012 Oct 24.
2
Imaging diagnosis: CT findings in a dog with intracranial hemorrhage secondary to angiostrongylosis.影像诊断:一只因血管圆线虫病继发颅内出血的犬的CT表现
Vet Radiol Ultrasound. 2012 Jul-Aug;53(4):420-3. doi: 10.1111/j.1740-8261.2011.01906.x. Epub 2011 Dec 19.
3
Detection of specific antibodies in dogs infected with Angiostrongylus vasorum.检测感染犬血管圆线虫的特异性抗体。
Vet Parasitol. 2012 Apr 30;185(2-4):216-24. doi: 10.1016/j.vetpar.2011.09.040. Epub 2011 Oct 8.
4
Canine and feline infections by cardiopulmonary nematodes in central and southern Italy.意大利中南部犬和猫的心丝虫感染。
Parasitol Res. 2011 Aug;109 Suppl 1:S87-96. doi: 10.1007/s00436-011-2405-5.
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Thoracic computed tomography findings in dogs experimentally infected with Angiostrongylus vasorum.实验感染血管圆线虫的犬的胸部计算机断层扫描结果
Vet Radiol Ultrasound. 2011 May-Jun;52(3):289-94. doi: 10.1111/j.1740-8261.2010.01776.x. Epub 2010 Dec 28.
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Improved detection of canine Angiostrongylus vasorum infection using real-time PCR and indirect ELISA.实时 PCR 和间接 ELISA 提高犬血管圆线虫感染检测。
Parasitol Res. 2011 Dec;109(6):1577-83. doi: 10.1007/s00436-011-2414-4. Epub 2011 May 3.
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Disseminated angiostrongylosis with massive cardiac and cerebral involvement in a dog from Italy.意大利一犬患有弥散性血管圆线虫病,伴有严重的心脏和脑部受累。
Parasitol Res. 2011 Aug;109(2):505-8. doi: 10.1007/s00436-011-2293-8. Epub 2011 Feb 24.
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An ELISA for sensitive and specific detection of circulating antigen of Angiostrongylus vasorum in serum samples of naturally and experimentally infected dogs.一种用于检测自然和实验感染犬血清中旋毛虫循环抗原的 ELISA 方法。
Vet Parasitol. 2011 Jun 30;179(1-3):152-8. doi: 10.1016/j.vetpar.2011.01.054. Epub 2011 Feb 2.
9
Angiostrongylus vasorum in 20 dogs in the province of Chieti, Italy.意大利基耶蒂省20只犬体内的管圆线虫
Vet Ital. 2011 Jan-Mar;47(1):77-88, 65-76.
10
Angiostrongylus vasorum infection in dogs: continuing spread and developments in diagnosis and treatment.犬类血管圆线虫感染:持续传播及诊断与治疗的进展
J Small Anim Pract. 2010 Dec;51(12):616-21. doi: 10.1111/j.1748-5827.2010.01000.x. Epub 2010 Oct 21.

自然感染犬的犬血管圆线虫病:临床处理及治疗后感染监测

Canine angiostrongylosis in naturally infected dogs: clinical approach and monitoring of infection after treatment.

作者信息

Paradies Paola, Schnyder Manuela, Capogna Antonio, Lia Riccardo Paolo, Sasanelli Mariateresa

机构信息

Department of Emergencies and Organs Transplantations, Veterinary Internal Medicine Unit, University of Bari, Strada Provinciale per Casamassima Km 3, 70010 Valenzano, Italy.

Institute of Parasitology, Vetsuisse Faculty, Winterthurerstr. 266a, CH-8057 Zürich, Switzerland.

出版信息

ScientificWorldJournal. 2013 Dec 29;2013:702056. doi: 10.1155/2013/702056. eCollection 2013.

DOI:10.1155/2013/702056
PMID:24459443
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3891238/
Abstract

Canine angiostrongylosis is an increasingly reported disease in Europe which can be fatal if left untreated. The wide range of clinical presentation along with the absence of pathognomonic alterations can make the diagnosis challenging; thus any additional information that may provide clues to an early diagnosis may be of value, in order to ensure adequate anthelmintic treatment. Aim of the study was to assess a clinicopathological scoring system associated with natural Angiostrongylus vasorum infection diagnosed in canine patients during clinical practice, to clinically and paraclinically monitor infected dogs after treatment, and to monitor the presence of L1 larvae in faecal samples by Baermann's test. Of the total 210 enrolled animals A. vasorum infection was diagnosed in 7 dogs. These dogs were clinically and paraclinically investigated and monitored after specific treatment. Further 3 symptomatic dogs were retrospectively included in the monitoring. Results suggest that the computed scoring system can help to increase the clinical suspicion of infection particularly in asymptomatic dogs before the onset of potentially lethal lesions. Data of faecal monitoring suggested that treatment may control parasite burden but be unable to eradicate infection. Thus, a continued faecal monitoring after treatment is advisable for identification of still infected or reinfected dogs.

摘要

犬血管圆线虫病在欧洲的报告病例日益增多,若不治疗可能致命。临床表现范围广泛且缺乏特征性改变,这使得诊断具有挑战性;因此,任何可能为早期诊断提供线索的额外信息都可能有价值,以便确保进行充分的驱虫治疗。本研究的目的是评估一种临床病理评分系统,该系统与临床实践中诊断出的犬自然感染血管圆线虫有关,用于在治疗后对感染犬进行临床和辅助临床监测,并通过贝尔曼氏试验监测粪便样本中L1幼虫的存在。在总共210只登记动物中,7只犬被诊断为感染血管圆线虫。这些犬在接受特定治疗后进行了临床和辅助临床调查及监测。另外3只出现症状的犬被回顾性纳入监测。结果表明,计算得出的评分系统有助于提高对感染的临床怀疑,特别是在潜在致命病变出现之前的无症状犬中。粪便监测数据表明,治疗可能控制寄生虫负荷,但无法根除感染。因此,建议在治疗后持续进行粪便监测,以识别仍被感染或再次感染的犬。