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[强迫症的异质性与共病性]

[Heterogeneity and comorbidity of obsessive-compulsive disorder].

作者信息

Zaudig M

机构信息

Psychosomatische Klinik Windach, Windach, Deutschland.

出版信息

Nervenarzt. 2011 Mar;82(3):290, 292, 294-6, passim. doi: 10.1007/s00115-010-2966-z.

DOI:10.1007/s00115-010-2966-z
PMID:21347693
Abstract

Although the DSM-IV-TR suggests that obsessive-compulsive disorder (OCD) is a coherent syndrome, scientific evidence offers a compelling case that OCD is highly heterogeneous and possibly composed of many different subtypes. OCD can display completely distinct symptom patterns thus making it difficult to identify a single "textbook" profile of OCD. The present state of research concerning subtyping is presented. There is a high comorbidity with depression and anxiety disorders, but all together data concerning OCD comorbidity are still not convincing. Currently obsessive-compulsive spectrum disorders (OCS) are described as a set of disorders lying on a continuum from compulsive to impulsive, with the unifying feature being an inability to regulate behaviour as a consequence of defects in inhibition. OCS disorders fall into three major clusters: impulsive disorders, disorders associated with appearance in bodily sensations, and neurological disorders characterized by repetitive behaviour. How these putative OCS disorders overlap with and are independent from obsessive-compulsive disorder itself is thoroughly discussed.

摘要

尽管《精神疾病诊断与统计手册第四版修订版》(DSM-IV-TR)表明强迫症(OCD)是一种连贯的综合征,但科学证据有力地证明,强迫症具有高度异质性,可能由许多不同的亚型组成。强迫症可表现出完全不同的症状模式,因此难以确定单一的“教科书式”强迫症特征。本文介绍了有关亚型分类的研究现状。强迫症与抑郁症和焦虑症的共病率很高,但关于强迫症共病的所有数据仍不具说服力。目前,强迫谱系障碍(OCS)被描述为一组从强迫到冲动连续分布的障碍,其统一特征是由于抑制缺陷而无法调节行为。强迫谱系障碍可分为三大类:冲动障碍、与身体感觉出现相关的障碍以及以重复行为为特征的神经障碍。本文深入讨论了这些假定的强迫谱系障碍如何与强迫症本身重叠以及相互独立。

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Frequency of obsessive-compulsive disorder in patients with multiple sclerosis: A cross-sectional study.多发性硬化症患者中强迫症的发病率:一项横断面研究。
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[Epidemiology and health care situation of obsessive-compulsive disorders].[强迫症的流行病学与医疗保健状况]

本文引用的文献

1
Predicting therapy outcome in patients with early and late obsessive-compulsive disorder (EOCD and LOCD).预测早发性和晚发性强迫症患者(早发性强迫症和晚发性强迫症)的治疗结果。
Behav Cogn Psychother. 2009 Oct;37(5):485-96. doi: 10.1017/S1352465809990294.
2
Meta-analysis of the symptom structure of obsessive-compulsive disorder.强迫症症状结构的荟萃分析。
Am J Psychiatry. 2008 Dec;165(12):1532-42. doi: 10.1176/appi.ajp.2008.08020320. Epub 2008 Oct 15.
3
Body dysmorphic disorder: treating an underrecognized disorder.躯体变形障碍:治疗一种未得到充分认识的疾病。
Nervenarzt. 2011 Mar;82(3):273-4, 276, 278, passim. doi: 10.1007/s00115-010-2960-5.
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4
Issues for DSM-V: how should obsessive-compulsive and related disorders be classified?《精神疾病诊断与统计手册》第五版面临的问题:强迫及相关障碍应如何分类?
Am J Psychiatry. 2007 Sep;164(9):1313-4. doi: 10.1176/appi.ajp.2007.07040568.
5
Familiality of factor analysis-derived YBOCS dimensions in OCD-affected sibling pairs from the OCD Collaborative Genetics Study.强迫症协作遗传学研究中受强迫症影响的同胞对中,基于因子分析得出的耶鲁布朗强迫症量表维度的家族性。
Biol Psychiatry. 2007 Mar 1;61(5):617-25. doi: 10.1016/j.biopsych.2006.05.040. Epub 2006 Oct 6.
6
Hoarding in obsessive-compulsive disorder: results from the OCD Collaborative Genetics Study.强迫症中的囤积行为:强迫症协作遗传学研究结果
Behav Res Ther. 2007 Apr;45(4):673-86. doi: 10.1016/j.brat.2006.05.008. Epub 2006 Jul 5.
7
A multidimensional model of obsessive-compulsive disorder.强迫症的多维模型。
Am J Psychiatry. 2005 Feb;162(2):228-38. doi: 10.1176/appi.ajp.162.2.228.
8
Treatment of obsessive-compulsive disorder in patients who have comorbid major depression.共病重度抑郁症患者的强迫症治疗
J Clin Psychol. 2004 Nov;60(11):1133-41. doi: 10.1002/jclp.20078.
9
Understanding and treating incompleteness in obsessive-compulsive disorder.理解与治疗强迫症中的不完整性。
J Clin Psychol. 2004 Nov;60(11):1155-68. doi: 10.1002/jclp.20080.
10
Distinct neural correlates of washing, checking, and hoarding symptom dimensions in obsessive-compulsive disorder.强迫症中洗涤、检查和囤积症状维度的不同神经关联。
Arch Gen Psychiatry. 2004 Jun;61(6):564-76. doi: 10.1001/archpsyc.61.6.564.