Fineberg Naomi A, Sharma Punita, Sivakumaran Thanusha, Sahakian Barbara, Chamberlain Sam R
Postgraduate School of Medicine, University of Hertfordshire, Queen Elizabeth II Hospital, Welwyn Garden City, UK.
CNS Spectr. 2007 Jun;12(6):467-82. doi: 10.1017/s1092852900015340.
It has been proposed that certain Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Axis I disorders share overlapping clinical features, genetic contributions, and treatment response and fall within an "obsessive-compulsive" spectrum. Obsessive-compulsive personality disorder (OCPD) resembles obsessive-compulsive disorder (OCD) and other spectrum disorders in terms of phenomenology, comorbidity, neurocognition, and treatment response. This article critically examines the nosological profile of OCPD with special reference to OCD and related disorders. By viewing OCPD as a candidate member of the obsessive-compulsive spectrum, we gain a fresh approach to understanding its neurobiology, etiology, and potential treatments.
有人提出，《精神疾病诊断与统计手册》第四版中的某些轴I障碍具有重叠的临床特征、遗传因素和治疗反应，属于“强迫性”谱系。强迫型人格障碍（OCPD）在现象学、共病、神经认知和治疗反应方面与强迫症（OCD）及其他谱系障碍相似。本文批判性地审视了强迫型人格障碍的疾病分类概况，并特别提及了强迫症及相关障碍。通过将强迫型人格障碍视为强迫谱系的候选成员，我们获得了一种全新的方法来理解其神经生物学、病因及潜在治疗方法。
