Institute of Experimental Botany ASCR, Prague, Czech Republic.
Curr Protein Pept Sci. 2011 Mar;12(2):148-55. doi: 10.2174/138920311795684959.
Current models of the plasma membrane (PM) organization focus on the lateral heterogeneity of the membrane and its relation to the cell function. Increasing evidence in mammals and yeast supports the direct relationship between PM lateral microdomains and specific cell processes and functions (nutrient transport, signaling, protein and lipid sorting, endocytosis, pathogen entry etc.). However, for the present the functional significance of an enrichment of specific proteins and possibly lipids in plant PM domains as well as the underlying molecular mechanism driving the lateral PM segregation remain unaddressed. Here we summarize recent findings on the plant PM organization and its role in signaling pathways, with the special emphasis on auxin transport.
目前的质膜（PM）组织模型侧重于膜的侧向异质性及其与细胞功能的关系。越来越多的证据表明，哺乳动物和酵母中 PM 侧向微区与特定的细胞过程和功能（营养物质运输、信号转导、蛋白质和脂质分拣、内吞作用、病原体进入等）之间存在直接关系。然而，目前尚不清楚植物 PM 区域中特定蛋白质和可能的脂质的富集的功能意义，以及驱动质膜横向分离的潜在分子机制。在这里，我们总结了最近关于植物 PM 组织及其在信号通路中的作用的发现，特别强调了生长素运输。
