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Br J Ophthalmol. 2011 Sep;95(9):1203-6. doi: 10.1136/bjo.2010.194217. Epub 2011 Feb 24.
Previous authors have suggested that an afferent pupillary defect (APD) may serve as an effective screening tool for some specific eye diseases, especially glaucomatous optic neuropathy, since the disease usually presents asymmetrically. Its success as a screening tool for glaucoma has never been previously prospectively evaluated in a large population.
In this study, the authors carry out assessments for the presence of APD as it relates to the diagnosis of glaucoma in an existing population-based eye study in southern India. The authors calculate the sensitivity and specificity for APD, both at the level of a village/household screening and in a more comprehensive/hospital setting, as it pertains to its ability to predict glaucomatous optic neuropathy.
The authors find that APD assessed via the swinging flashlight test is a poor screening tool for glaucoma in this setting.
之前的作者提出，传入瞳孔缺陷（APD）可能作为一种有效的筛查工具，用于某些特定的眼部疾病，特别是青光眼性视神经病变，因为这种疾病通常呈不对称性发生。APD 作为青光眼的筛查工具，其在大规模人群中的前瞻性评估以前从未进行过。
在这项研究中，作者在印度南部的一项基于人群的眼部研究中，对 APD 的存在进行评估，以确定其与青光眼的诊断关系。作者计算了 APD 的灵敏度和特异性，包括在村落/家庭筛查层面，以及更全面/医院层面，以评估其预测青光眼性视神经病变的能力。
作者发现，在这种情况下，通过晃动检眼镜测试评估的 APD 是一种较差的青光眼筛查工具。
