The Ludwig Boltzmann Institute for Retinology and Biomicroscopic Laser Surgery, Vienna, Austria.
Br J Ophthalmol. 2011 Nov;95(11):1552-4. doi: 10.1136/bjo.2010.194670. Epub 2011 Feb 24.
Spectral domain optical coherence tomography (SD OCT) is of increasing importance and is gradually replacing time domain OCT (TD OCT). Our aim was to determine a formula to convert Stratus OCT (TD OCT) to Cirrus OCT (SD OCT) retinal thickness.
Central retinal thickness (CRT) and retinal volume (RV) were obtained by the macular thickness program of Stratus OCT and the cube 512 × 128 program of Cirrus OCT in patients with exudative age-related macular degeneration (AMD). Algorithm line failures were corrected. A linear model with Stratus OCT CRT as fixed factor and Cirrus OCT CRT as dependent variable was applied to calculate the conversion formula.
OCT examinations of 104 eyes of 104 patients were reviewed and corrected when necessary. Stratus and Cirrus OCT CRT were significantly correlated (p<0.0001). For CRT the formula Cirrus CRT=58.63+0.94 × Stratus CRT was calculated. The correlation was significantly influenced by the height of the CRT values (p<0.0001), but not by whether correction was necessary. For RV the formula Cirrus OCT RV=3.098+0.98 × Stratus OCT RV was calculated.
Stratus OCT and Cirrus OCT use a different posterior reference line within the hyper-reflective band of the outer retina. Therefore a conversion formula is necessary to compare Stratus and Cirrus OCT CRT values, and this has been determined in our study.
光谱域光相干断层扫描（SD OCT）的重要性日益增加，并且正在逐渐取代时域光相干断层扫描（TD OCT）。我们的目的是确定一种将 Stratus OCT（TD OCT）转换为 Cirrus OCT（SD OCT）视网膜厚度的公式。
在渗出性年龄相关性黄斑变性（AMD）患者中，使用 Stratus OCT 的黄斑厚度程序和 Cirrus OCT 的立方 512×128 程序获得中心视网膜厚度（CRT）和视网膜体积（RV）。对算法线失败进行了校正。使用 Stratus OCT CRT 作为固定因子，Cirrus OCT CRT 作为因变量的线性模型来计算转换公式。
对 104 例 104 只眼的 OCT 检查进行了回顾，并在必要时进行了校正。Stratus 和 Cirrus OCT CRT 显著相关（p<0.0001）。对于 CRT，计算出 Cirrus CRT=58.63+0.94×Stratus CRT 的公式。相关性显著受 CRT 值高度的影响（p<0.0001），但不受校正是否必要的影响。对于 RV，计算出 Cirrus OCT RV=3.098+0.98×Stratus OCT RV 的公式。
Stratus OCT 和 Cirrus OCT 在视网膜外光反射带内使用不同的后参考线。因此，需要一个转换公式来比较 Stratus 和 Cirrus OCT CRT 值，我们在本研究中已经确定了该公式。
