Kılıçgün Ali, Sarıkaş Necla G, Korkmaz Tanzer, Saydam Ozkan, Boran Cetin, Boztaş Güledal
Department of Thoracic Surgery, School of Medicine, University of Abant İzzet Baysal, Bolu, Turkey.
J Cardiothorac Surg. 2011 Feb 27;6:20. doi: 10.1186/1749-8090-6-20.
Air leakage and hemorrhage are important causes of morbidity and mortality in operations and traumas of the lung. Ankaferd Blood Stopper is a herbal product used for stopping hemorrhage. In our study, we investigated the efficacy of Ankaferd Blood Stopper in the prevention of air leakage in the lung and bleeding.
A total of twenty-one Wistar-Albino rats weighing 240 ± 20 grams were used in our study. An equal amount of injury was created in all groups by performing left thoracotomies. No interventions were made on tissue injury in the first group, and suturing was performed in the second group, and Ankaferd was applied in the third group. Air leakage and duration of bleeding were recorded in all groups.
A statistically significant difference was found between the three groups in terms of air leakage time (p = 0,0001) and bleeding time (p = 0,0001). While a significant effect of Ankaferd was detected in terms of air leakage compared to standard surgery (p = 0,017), no difference was found in terms of bleeding time.
Ankaferd Blood Stopper ceases the air leakage in the lung parenchyma significantly and effectively. No significant difference is seen compared to the standard surgery group, although it ceases bleeding significantly.
漏气和出血是肺部手术和创伤中发病和死亡的重要原因。安卡非德止血剂是一种用于止血的草药产品。在我们的研究中，我们调查了安卡非德止血剂在预防肺部漏气和出血方面的疗效。
我们的研究共使用了21只体重240±20克的Wistar白化大鼠。通过左胸切开术在所有组中造成等量的损伤。第一组不对组织损伤进行干预，第二组进行缝合，第三组应用安卡非德。记录所有组的漏气情况和出血持续时间。
三组在漏气时间（p = 0.0001）和出血时间（p = 0.0001）方面存在统计学上的显著差异。与标准手术相比，安卡非德在漏气方面有显著效果（p = 0.017），但在出血时间方面没有差异。
安卡非德止血剂能显著有效地停止肺实质内的漏气。与标准手术组相比，虽然它能显著止血，但未见显著差异。
