Department of Oral Diagnosis, Medicine and Radiology, MGV's K.B.H. Dental College and Hospital, Nashik, Maharashtra, India.
Oral Oncol. 2011 Apr;47(4):231-6. doi: 10.1016/j.oraloncology.2011.01.009. Epub 2011 Feb 24.
The adenoid cystic carcinoma is a relatively rare epithelial tumor of the major and minor salivary glands, accounting for about 1% of all malignant tumor of the oral and maxillofacial region. Although it presents a widespread age distribution, peak incidence occurs predominantly among women, between the 5th and 6th decades of life. The clinical and pathological findings typical of this tumor include slow growth, perineural invasion, potential local recurrence and distant metastasis. Histopathologically it is composed of basaloid cells with primarily myoepithelial/basal cell differentiation. It presents three patterns, cribriform, tubular and solid; the solid type is related to a poor prognosis contrary to the cribriform type, which has a better prognosis. Surgical excision with wide margins is the treatment of choice, if it metastasizes to lymph nodules, post surgical radiotherapy is recommended. We presented herein the case of a 45 year old female patient who presented a palatal lesion, which was treated with surgery and radiotherapy as an additional treatment. We also described a brief literature review of adenoid cystic carcinoma.
腺样囊性癌是一种相对罕见的涎腺上皮性肿瘤，约占口腔颌面部恶性肿瘤的 1%。尽管其发病年龄分布广泛，但主要发生在女性，5 至 6 十年代为发病高峰。该肿瘤的典型临床表现和病理学特征包括生长缓慢、神经周围侵犯、局部复发和远处转移的潜能。组织病理学上由基底样细胞组成，主要为肌上皮/基底细胞分化。它有三种类型：筛状、管状和实体型；与预后不良相关的是实体型，而预后较好的是筛状型。广泛切除是首选的治疗方法，如果发生淋巴结转移，建议术后进行放射治疗。我们在此介绍了一位 45 岁女性患者的病例，她的硬腭出现病变，采用手术和放疗联合治疗。我们还简要回顾了腺样囊性癌的文献。
